Here we have reviewed top numbing creams for painless cannulation and vaccination.

Many people fear cannulation—a technique in which cannula, a needle shaped tube, is placed inside a vein to get sampling of blood and delivering of fluids, medications and blood products to the body. Nearly 50 million Americans admitted to fear of needles (trypanophobia).

This is why a local anesthetic cream is always recommended by the physicians to deal with such fear. Actually, local anesthetic cream dulls the pain receptors locating beneath the skin so that they don’t carry pain signals to the brain. In this way, you don’t feel anything done to your skin.

There are plenty of numbing creams to choose from. However, it is important to choose the right numbing cream for cannulation.

Here we have rounded up such numbing creams….


Being in the market for over 20 years, Thera-Gesic is water based numbing cream containing menthol and methyl salicylate as its main ingredients. Its efficiency is determined by the layers you apply to the skin. For example, one layer of the cream delivers mild effect while three layers of the cream is for the stronger effect.


Blue Emu is a super strength cream that not only numbs the skin, but also feels great on dry, chapped and weathered skin. It contains emu oil and aloe vera which heal your swollen and aching skin due to cannulation. The cream is also used to ease muscle and joint pain.


Aspercreme is a pain relieving cream with 4% lidocaine. It claims to target more pain receptors than any other topical analgesics. It numbs your skin without irritation and burning sensation.

Numb 520:

Numb 520 contain 5% lidocaine and helps relieve discomfort and itching. It also provides relief from pain, soreness and burning. According to the manufacturer’s claim, the cream delivers numbing effect within 3-5 minutes of application which would be last about 1 hour. The cream has got 4 star rating at Amazon, making it a trustworthy cream for cannulation.


The numbing cream is said to be made by a leading orthopedic surgeon and a physical therapist. The cream contains menthol, aloe, boswellia, vitamin E, and MSM. The numbing efficiency largely rests on menthol which cooling sensation counters pain signals targeting the brain.

MyoMed Pro:

MyoMed Pro claims to be the “best all natural, homeopathic pain relief therapy.” According to its website, it contains the potent blend of homeopathic and powerful essential oils. The product addresses the pain linked to restless legs syndrome, shingles, bruises, arthritis, back, shoulder and knee.

Dr. Pergolizzi’sOxyRub:

Oxyrub has got 3.5 star customer ratings at Amazon. It claims to give guaranteed relief from pain of arthritis, bursitis, tendinitis, backache, muscle ache, and other conditions.Oxyrub contains menthol as its main ingredient to soothe the pain.

So these are our best picks of numbing cream for cannulation and vaccination. Whatever you choose, make sure to read the guidelines before using the cream. Or it is better if you consult your physician.